In the near future, when people on all seven continents can use AI to heal or prevent musculoskeletal pain, we could very well look to a large room at the back of the Education Complex at UCF and say this is one of the places where everything began to change. It 麻豆精品 S檚 an interesting space. In fact, if you miss the sign over a threshold in the lobby (Institute of Exercise Physiology and Rehabilitation Science) you might wonder if you 麻豆精品 S檝e walked into a lab, a rehab clinic, or a fitness center. There are treadmills and mats, resistance bands and treatment tables, and voices of researchers in mid-instruction.

In an area set apart with privacy dividers, Assistant Professor Colby Mangum rolls a chair up to a portable ultrasound machine and a laptop. Aside from the signage, these are the first giveaways that you 麻豆精品 S檝e entered an important intersection of research, technology, physical health, and profound possibilities.

麻豆精品 S淲e want the lab to be as 麻豆精品 S榬eal world 麻豆精品 S as possible, so we can address real problems with real patients, 麻豆精品 S Mangum says of what she calls the REhabilitation, Athletic assessment and DYnamic imaging (READY) Lab. 麻豆精品 S淚t 麻豆精品 S檚 the only way to make a genuine impact on the future of musculoskeletal health. 麻豆精品 S

麻豆精品 S淲e want the lab to be as 麻豆精品 S榬eal world 麻豆精品 S as possible, so we can address real problems with real patients. 麻豆精品 S 麻豆精品 S Colby Mangum, assistant professor

Before diving into her research, it 麻豆精品 S檚 helpful to know something about the researcher. Mangum 麻豆精品 S檚 career aligns with the cues in this active lab. She started as an athletic trainer while also becoming an expert in the use of ultrasound imaging as a researcher so she could blend all of her interests into finding better answers for people with chronic pain and for those who want to prevent it. In 2018, that personal mission led her to UCF where she was asked to grow the athletic training research agenda at the College of Health Professions and Sciences. Today, thanks to internal seed funding, she 麻豆精品 S檚 ramping up her research focus on improving diagnostics and treatment courses for the most widespread pain in the world: Low back pain, which affects more than 600 million people globally.

Mangum has seen enough cases of lower back pain to spark her curiosity about the source of the pain and how muscles around the lower back and spine are affected.

麻豆精品 S淚t oftentimes seems to connect to the core, 麻豆精品 S she says. 麻豆精品 S淚 麻豆精品 S檓 talking about well-conditioned athletes, younger people and older people. It goes back to an imbalance in those three layers of abdominal muscles: external obliques, internal obliques, and transverse abdominis. 麻豆精品 S

MRI and CT are the most often used imaging modalities to assess musculoskeletal conditions, but MRI is expensive and CT exposes patients to radiation. In addition, neither is good at imaging tissue movement, which can yield important information about the physical properties of tissues.  Ultrasound, on the other hand, is safe, low cost, portable, and can capture tissue dynamics during rehab sessions.

麻豆精品 S淯ltrasound has the potential to unlock answers, especially for low back pain for a large population scale, 麻豆精品 S Mangum says, 麻豆精品 S渂ut first we need to overcome some issues we face. 麻豆精品 S

Those issues primarily come down to the training it takes for clinicians and researchers to acquire good quality ultrasound images and the time it takes for them to manually measure ultrasound readouts. There 麻豆精品 S檚 also high subjectivity in those measurements. Mangum has believed for years that some ultrasound automation would be the only way to reach hundreds of millions of people and begin making a transformational impact. She also knew she couldn 麻豆精品 S檛 do something that big alone in this lab.

麻豆精品 S淚t became clear that if I could collaborate with an AI expert, 麻豆精品 S Mangum says, 麻豆精品 S渋t would be the gamechanger. 麻豆精品 S

UCF College of Health Professions and Sciences Assistant Professor Colby Mangum  (left) and College of Medicine Associate Professor Laura Brattain (right)

The Power of Two

麻豆精品 S淭he first time I spoke with Laura, I sensed her enthusiasm for this project, 麻豆精品 S Mangum says of Laura Brattain, the College of Medicine associate professor with whom she 麻豆精品 S檒l collaborate over the course of the next year. 麻豆精品 S淲e recognize the value of our complementary expertise 麻豆精品 S mine with ultrasound and patient care in a clinical setting and hers in applying AI to healthcare. 麻豆精品 S

Mangum calls Brattain 麻豆精品 S渁 powerhouse 麻豆精品 S because of her training as a biomedical engineer and fascination with medicine. While at MIT, Brattain developed portable emergency care technologies and, not so coincidentally, AI algorithms for analyzing ultrasound images for disease diagnostics and procedure guidance. She joined the in 2024 as an associate professor in the College of Medicine with an affiliated appointment in the College of Engineering and Computer Science 麻豆精品 S a position conducive for translational AI research.

麻豆精品 S淭he AI initiatives at UCF provide me with a bigger platform to innovate with clinicians and turn research into something impactful, 麻豆精品 S Brattain says. 麻豆精品 S淎s soon as I arrived, I found myself in this great ecosystem, collaborating with hospitals and with researchers who have clinical experience, like Colby. 麻豆精品 S

The combined skillsets of Mangum and Brattain and the far-reaching potential of their low back pain project will start with a seed grant of $12,000 from UCF and a matching grant from the College of Medicine. The funding will allow them to acquire ultrasound data from both individuals with and without a history of lower back pain, use AI and human raters to analyze the images, then establish if there is reliability and agreement between the manual and automated analysis. AI is certainly faster, but is it just as accurate and consistent? Could it one day eliminate the training needed by ultrasound operators as well as improve the data and ultimately, the outcomes?

麻豆精品 S淭he AI initiatives at UCF provide me with a bigger platform to innovate with clinicians and turn research into something impactful. 麻豆精品 S 麻豆精品 S Laura Brattain, associate professor

The researchers will work with students (a health sciences major and a biomedical AI doctoral student) to generate solid preliminary results before seeking larger external financial support. However, the numbers behind these initial dollar signs are not the story.

麻豆精品 S淚 already have the necessary space and equipment for the work, 麻豆精品 S Mangum says. 麻豆精品 S淭he strength of the seed funding is in how it merges our expertise so we can stretch the boundaries of what people are capable of doing with ultrasound. 麻豆精品 S

Mangum demonstrates the way a typical ultrasound has been used to address low back pain. A patient lies on a table while the technician uses a transducer to take pictures of the three layers of abdominal muscles. While the study will take similar static images, the UCF researchers will also capture additional, dynamic images with the patient 麻豆精品 S檚 body in motion 麻豆精品 S an approach that until now has not been fully explored by others.

麻豆精品 S淲e know the problem is typically a muscle out of balance somewhere in there, 麻豆精品 S she says, pointing to the entire picture on her screen. To pinpoint the 麻豆精品 S渟omewhere, 麻豆精品 S the technician has to find the correct orientation of the ultrasound probe and take time to make the manual measurements, which can potentially lead to inconsistencies and delays in rehab.

麻豆精品 S淎s soon as I started doing ultrasound imaging in graduate school, I thought, 麻豆精品 S榯here has to be a better way to get these measurements, 麻豆精品 S 麻豆精品 S Mangum says. 麻豆精品 S淎I could certainly be the way. By implementing it into our existing tools, it seems there is a strong potential for improving speed, accuracy and outcomes. 麻豆精品 S

It 麻豆精品 S檚 easy to understand why these possibilities excite a clinician like Mangum. But what about Brattain, the biomedical engineer?

麻豆精品 S淚 麻豆精品 S檓 currently the chair of AI Community of Practice at the American Institute of Ultrasound for Medicine. Just like Colby, I 麻豆精品 S檓 a strong proponent of AI-driven ultrasound applications. I 麻豆精品 S檓 an avid pickleball player and work out daily. Before taking on this project, I did a survey on the most common physical issues for active people 麻豆精品 S low back pain kept coming up. If my skills with AI can help standardize musculoskeletal ultrasound, that means we have potential to improve the current workflow for low back pain rehabilitation and we can eventually scale this up to personalized at-home care and expand to other musculoskeletal injuries. The potential return on investment is high. 麻豆精品 S

Better Lives for People Far and Near

Mangum and Brattain 麻豆精品 S檚 skill sets are as complementary as their perspectives. For example, take their concept of scale, which Brattain mentioned.

麻豆精品 S淓nd users might access this kind of ultrasound technology on something like a smartwatch, 麻豆精品 S she says. 麻豆精品 S淪o, it would be available anywhere, even in rural communities and in extreme environments like the battlefield and in space. 麻豆精品 S

From her lab space near the center of campus, Mangum says, 麻豆精品 S淲e could walk just beyond this door and find people on campus with low back pain. 麻豆精品 S This is why her lab will become a low back pain research clinic in the coming months. The 40 participants for the project will be a mix of people at UCF and from the greater community. Mangum and her student researcher will perform ultrasounds and send the images to Brattain and her team, who will conduct the AI analysis.

麻豆精品 S淎nd then we 麻豆精品 S檙e off to the races, 麻豆精品 S Mangum says. 麻豆精品 S淏y leveraging each other 麻豆精品 S檚 strengths, we can improve rehab, apply what we learn to other musculoskeletal needs, and help more people. That 麻豆精品 S檚 where we can go with this because of the power of collaboration. 麻豆精品 S